The process by which cells adjust their structure and function according to environmental stimu lus created by their physical environment. This translation of mechanical signals into biochemical ones, is responsible for a number of senses and physiological processes in the body, including proprioception, touch, balance, and hearing.

When we move, we are not only rearranging our spine and peripheral parts, but we are also organizing the very smallest structures that our bodies are comprised of, our cells. Our entire body is made up of cells. The cells create a matrix, and in order of organizational complexity then create tissues, organs, organ systems and finally the whole body.

Our cells have their own cytoskeleton that holds them up against the Earth's gravitational force. At various times, other forces load them as well, such as the push/pull force of objects in our physical world. There are three forms of mechanical input to our bodies: external pressures, frictions and tractioning.